Developmental Evolution: Torso — a Story with Different Ends?
نویسنده
چکیده
The Torso pathway patterns the ends of the Drosophila embryo. Now, it has been found to control axis elongation in the short germ insect Tribolium. This result raises the issue of the ancestral function of the Torso pathway and its evolution.
منابع مشابه
Reconstitution of Torso signaling in cultured cells suggests a role for both Trunk and Torso-like in receptor activation.
Formation of the Drosophila embryonic termini is controlled by the localized activation of the receptor tyrosine kinase Torso. Both Torso and Torso's presumed ligand, Trunk, are expressed uniformly in the early embryo. Polar activation of Torso requires Torso-like, which is expressed by follicle cells adjacent to the ends of the developing oocyte. We find that Torso expressed at high levels in ...
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Activation of receptor tyrosine kinases triggers many developmental decisions, yet we do not understand how activation of a single receptor can be transduced into different cell responses. The torso pathway in Drosophila provides a model to address this issue since it generates more than one response in the embryo. The torso receptor tyrosine kinase is activated at the embryonic poles under the...
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ورودعنوان ژورنال:
- Current Biology
دوره 16 شماره
صفحات -
تاریخ انتشار 2005